Goat Secondary Antibodies
Cayman Chemical Amygdalin, Purity: ≥98%, CAS: 29883-15-6, 25 g
A glycoside with diverse biological activities; induces cell cycle arrest at the G0/G1 phase, decreases cyclin A and Cdk2 levels, and inhibits cell growth in UMUC-3, RT112, and TCCSUP bladder cancer cells from 1.25-10 mg/ml; reduces the number of primary microtubules and microvessels in aortic rings isolated from rats with streptozotocin-induced diabetes at 3 mg/kg; reduces triglyceride, total cholesterol, and LDL levels and aortic sinus plaque area in an LDLR-/- mouse model of atherosclerosis; reduces production of TNF-α, IL-1β, and IL-6 as well as neutrophil and macrophage infiltration in BALF in a mouse model of LPS-induced acute lung injury
Cayman Chemical Dehydroevodiamine (hydrochloride), Purity: ≥98%, CAS: 111664-82-5, 250 mg
An alkaloid with diverse biological activities; inhibits LPS-induced secretion of PGE2 in RAW 264.7 mouse macrophages at 30 μM; reduces the upstroke velocity, action potential amplitude, and contractile force of electrically-stimulated primary human atrial trabeculae from 0.1-0.3 μM; decreases MAP by ~30% in rats at 10 mg/kg; inhibits amyloid-β (25-35)-induced amnesia and increases latency to step-through in a passive avoidance test in mice at 1.5 mg/kg
Cayman Chemical C6 NBD Lthreo CeramIded18100ug
A fluorescently tagged sphingolipid; rapidly transferred between liposomes, labels the Golgi apparatus, and is metabolized to C6 NBD sphingomyelin in BHK cells and V79 fibroblasts
Cayman Chemical C2 L-threo Ceramide (d18:1/2:0), Purity: ≥98%, CAS: 143615-69-4, 1 mg
A cell-permeable analog of naturally occurring ceramides; stimulates cholesterol efflux in CHO cells expressing the human ABCA1 receptor (10 μM); inhibits IL-4 production by 17% in EL4 T cells stimulated with PMA when used at a concentration of 10 μM; induces cell cycle arrest in the G0/G1 phase and a 7-fold increase in sphingosine accumulation as well as inhibits growth of HL-60 leukemia cells
Cayman Chemical 1,2,3-Tri-6(Z)-Octadecenoyl Glycerol, Purity: ≥98%, CAS: 3296-43-3, 50 mg
A triacylglycerol; has been found in plant seed oils
Cayman Chemical PergolIdemesylate 250mg
A potent and selective Syk inhibitor (IC50 4 nM) inhibits 92 of Syk activity while other kinases retain 70 activity at a concentration of 50 nM in a panel of 270 kinases inhibits convulxin-induced aggregation of human platelet-rich plasma (IC50 2.5 M) prevents thrombosis in a transgenic mouse model of heparin-induced thrombocytopenia induces CLL B cell apoptosis and inhibits the secretion of chemokines CCL3 CCL4 and CXCL13 inhibits CLL B cell chemotaxis and pseudoemperipolesis
Cayman Chemical Fludrocortisone Acetate, Purity: ≥98%, CAS: 514-36-3, 500 mg
A mineralocorticoid agonist; promotes sodium retention in rats in a dose-dependent manner with 37% of sodium excreted compared with control when used at a dose of 5 µg/animal
American Research Products Inc Anti HPSE2 Antibody
Anti-HPSE2 Rabbit Polyclonal Antibody Carboxyterminal end
American Research Products Inc Anti SPPL2C Antibody
Anti-SPPL2C Rabbit Polyclonal Antibody First cytoplasmic loop
ABclonal Technology 594 anti-Human CD170/Siglec-5
This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes macrophages and neutrophils Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion
Cayman Chemical metafluoroMethylamInorex500ug
An analytical reference standard that is structurally similar to known stimulants; intended for research and forensic applications
Cayman Chemical 1,3-Dipentadecanoyl Glycerol, Purity: ≥95%, CAS: 59891-25-7, 50 mg
A diacylglycerol; has been used as an internal standard for the quantification of ceramides and diacylglycerols in rat soleus muscle by LC-MS/MS
Cayman Chemical Benzydamine (hydrochloride), Purity: ≥95%, CAS: 132-69-4, 5 g
An NSAID; decreases the viability of THP-1, Saos-2, and HGF-1 cells (IC50s = 59.08, 30.79, and 52.06 µg/ml, respectively); reduces LPS-induced increases in the levels of IL-6 and TNF-α secreted by THP-1 cells at 10 µg/ml; decreases PGE2 and PGF1α levels in unstimulated or IL-1β- or TNF-α-stimulated primary human gingival fibroblasts at 1 µM; reduces hydrochloric acid levels and increases mucin levels in gastric juices isolated from rats at 100 mg/kg; inhibits carrageenan-induced paw edema in rats at an oral dose of 60 mg/kg or applied topically at 3% (w/w)
Cayman Chemical 3-Hydroxyisobutyrate (sodium salt), Purity: ≥95%, CAS: 1219589-99-7, 250 mg
An intermediate in the metabolism of valine; increases fatty acid uptake by HUVECs at 0.1-100 mM; increases fatty acid uptake and lipid accumulation in mouse skeletal muscle; levels are increased in db/db diabetic mice and in humans with diabetes; human plasma levels are increased in obesity and correlate with a future risk of type 2 diabetes; human serum levels decrease following an exercise regimen of 2.5 hours of running for three days
Cayman Chemical AP-237 (hydrochloride), Purity: ≥98%, CAS: 17730-82-4, 5 mg
An analytical reference standard categorized as an opioid; intended for research and forensic applications